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Reproductive Immunology:

Fertility and Pregnancy

Fertility is directly connected to the health of the immune system, which plays a critical role in supporting pregnancy. A balanced, well-regulated immune response ensures that the body can successfully conceive, sustain a pregnancy, and allow a developing baby to grow without complications.

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At Regenerative Immunology, we specialize in immune system optimization to address the root causes of infertility, recurrent miscarriages, and pregnancy complications.

Reproductive Immunology:

couple at fertility appointment

Reproductive immunology medicine is a specialized field that focuses on the interaction between the immune system and reproductive processes, particularly in the context of fertility, pregnancy, and related complications.

 

It focuses on identification and treatment of the immune system functions and components which can impact fertility outcomes, such as infertility, recurrent miscarriages, preterm deliveries, and conditions like pre-eclampsia.

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 Our treatment protocols affect how immune responses support successful conception, implantation, and gestation.

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  • Immune Problems in Fertility: Reproductive immunology addresses various immune-related issues that can lead to infertility, failed IVF procedures, or recurrent pregnancy loss. These problems are categorized from mild (Category 1) to severe (Category 5), encompassing issues like genetic compatibility (HLA), blood clotting problems, autoimmune responses to embryos or sperm antigens, and increased activity of certain immune cells like natural killer (NK) cells.

  • Diagnostic Testing: Immune testing is crucial in reproductive immunology to identify specific immune factors contributing to fertility challenges. Tests such as DQ alpha testing for genetic compatibility, leukocyte antibody detection for broader compatibility assessment, reproductive immunophenotyping for NK cell presence evaluation, and various cell designation tests are used to pinpoint immune dysregulation.

  • Integrative Treatment: Natural and Ancient medicine offers treatments for reproductive immunological factors by addressing immune system imbalances through acupuncture, herbal medications, reproductive organ massage, nutrition therapy, and dietary adjustments. These methods aim to restore immune balance and support reproductive health.

  • Photobiodynamic Treatment: low intensity red laser provides an excellent anti-inflammatory and regenerative effect by stimulation of the immune cells (fibroblasts and macrophages) and naturally reversing chronic pathogenic processes. It was found to activate mitochondria and enhancing cell survival and function. For years PBD was used in orthopedics, pain management and even neurologic treatments. Now a fascinating report opens up the horizons for fertility and pregnancy management. Our clinic purchased one of the best cold red laser and we see a tremendous success.

  • Immune Reboot: over 10 years our clinic achieves nearly 90% recovery for patients with autoinflammation. This treatment produced healthy spontaneous pregnancies in at least 15 patients, and helped with IVF treatments in many families. Now it is a standard management for fertility and pregnancy support. 

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In summary, reproductive immunology medicine delves into the intricate relationship between the immune system and reproduction to address fertility challenges and optimize pregnancy outcomes through a combination of inflammation control, spiritual treatment, and overall increase in body functioning.

How the Immune System Affects Fertility

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Achieve a Healthy Pregnancy Naturally

If you're struggling with infertility or recurrent miscarriages, focusing on immune health can dramatically improve your chances of conceiving and carrying a healthy baby to term.

 

At Regenerative Immunology, we help couples achieve their dream of parenthood by optimizing the body's natural ability to sustain a pregnancy.

The Link Between Fertility & Immune Health

Fertility is directly connected to the health of the immune system, which plays a critical role in supporting pregnancy. A balanced, well-regulated immune response ensures that the body can successfully conceive, sustain a pregnancy, and allow a developing baby to grow without complications.

At Regenerative Immunology, we specialize in immune system optimization to address the root causes of infertility, recurrent miscarriages, and pregnancy complications.

How the Immune System Affects Fertility

1. Immune Hyperactivity & Unexplained Infertility

✔ An overactive immune system can mistakenly attack a developing embryo, leading to implantation failure or recurrent pregnancy loss.
✔ Conditions like autoimmune disorders, chronic inflammation, and allergies can signal underlying immune imbalances that interfere with fertility.

2. Chronic Inflammation & Hormonal Disruptions

✔ Inflammation can affect the ovaries, fallopian tubes, and endometrial lining, making it harder for an embryo to implant and thrive.
✔ Gut health, diet, and environmental toxins contribute to chronic inflammation, which functional medicine can help reverse.

3. The Role of Epigenetics & Immune Balance in Pregnancy

✔ Epigenetics plays a key role in fetal development, meaning lifestyle, nutrition, and immune function influence gene expression for a healthy baby.
✔ By addressing immune dysfunction before conception, we improve the chances of a healthy pregnancy and baby.

Regenerative Immunology’s Approach to Fertility

✔ Comprehensive immune and fertility testing to identify imbalances.
✔ Gut microbiome and inflammation control to optimize reproductive health.
✔ Detoxification from environmental toxins and mold that may disrupt fertility.
✔ Personalized treatment plans including SLIT drops, photobiomodulation, and targeted immune support therapies.

What to Expect From Reproductive Immunology Appointment?

First we need to collect all information about your previous management and diagnosis. For that we need:

  • Medical records from your primary care office

  • Medical records from your infertility clinic(s)

  • Your story. It will be extremely helpful if you summarize your journey to having the baby in a short story with timelines.

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Next, we will schedule a consultation appointment where Doctor will decide what type of testing needs to be done. Dependent on what was tested before and your story, we have multiple tests and laboratories we use.

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Now, based on the results of the tests Doctor will discuss a treatment plan:

  • Natural Fertility Boost

  • Integrative Support of Reproductive Treatment

  • Pregnancy Support

  • Miscarriage Treatment

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Based on our experience we highly recommend couple treatment. 

Get Healthy Baby With Us!

At ImmuneLine you will experience the integrative treatment were spiritual and body treatment give you the ability to have a baby. Our couples love the experience and a result!

healthy baby

Red-NIR-IR laser 
is a Non-Invasive Fertility Treatment 

✅ PBM in Female Fertility

Several studies and clinical experiences suggest that PBM may:

  1. Improve ovarian function

    • Enhances mitochondrial activity → better ATP production in oocytes

    • May improve ovarian blood flow → increased oxygen and nutrient supply

  2. Improve endometrial receptivity

    • Improves microcirculation to the uterus

    • Enhances endometrial thickness (important for implantation)

  3. Regulate hormonal balance

    • Indirect effects via hypothalamic-pituitary-ovarian (HPO) axis

    • Can help in cases of PCOS, luteal phase deficiency, etc.

  4. Reduce oxidative stress

    • Many infertility issues (age-related infertility, endometriosis, recurrent miscarriage) are linked to oxidative stress → PBM helps restore redox balance.

  5. Support IVF outcomes

    • Studies have shown higher pregnancy and live birth rates when PBM is integrated before and during IVF cycles.

✅ PBM in Male Fertility

  1. Enhance sperm quality

    • Increases motility, morphology, and concentration

    • Reduces DNA fragmentation index (DFI)

    • Reduces oxidative stress in seminal plasma

  2. Boost testosterone production

    • Some evidence suggests PBM may stimulate Leydig cells to improve testosterone synthesis indirectly benefiting spermatogenesis.

  3. Improve blood flow to testes

    • Better oxygenation and nutrient delivery

✅ Common Protocols (Used in Studies & Clinics)

ParameterTypical for Fertility Boost: Wavelength630–850 nm

Dose3–8 J/cm² per session

Sessions2–3x weekly for 4–8 weeks

Application: Lower abdomen (uterus, ovaries), lumbar spine, testes (in males), and acupoints

✅ Notes:

  • In women, PBM is often started in the follicular phase and continued until ovulation or embryo transfer.

  • In men, a minimum of 6 weeks is often needed due to the spermatogenesis cycle (~64 days).

  • Safety: PBM is non-invasive, painless, and safe when applied correctly.

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